Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.57 |
| ▸ | CASP6 | P55212 | 18/20 | 0.57 |
| ▸ | CASP8 | Q14790 | 18/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557122 | 0.89 | CASP3 (0.57) | CASP3CASP6CASP8 | |
| SCHEMBL4556814 | 0.86 | CASP3 (0.41) | CASP3CASP6CASP8 | |
| SCHEMBL4556826 | 0.84 | CASP3 (0.59) | CASP3CASP6CASP8 | |
| SCHEMBL4556832 | 0.83 | CASP3 (0.56) | CASP3CASP6CASP8 | |
| SCHEMBL4556546 | 0.83 | CASP3 (0.60) | CASP3CASP6CASP8 | |
| SCHEMBL4551966 | 0.81 | CASP3 (0.54) | CASP3CASP6CASP8 | |
| SCHEMBL6054149 | 0.79 | CASP1 (0.39) | CASP3CASP6CASP8 | |
| SCHEMBL4557103 | 0.78 | CASP3 (0.61) | CASP3CASP6CASP8 | |
| SCHEMBL5669141 | 0.77 | CASP3 (0.61) | CASP3CASP6CASP8 | |
| SCHEMBL4556651 | 0.76 | CASP3 (0.60) | CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091930-B1 | C-TERMINAL MODIFIED OXAMYL DIPEPTIDES AS INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS INC (US) | 2006-12-13 | — | — | EP | claimed |
| US-6544951-B2 | Antiinflammatory agents; autoimmune diseases, nervous system degradation | IDUN PHARMACEUTICALS, INC. | 2003-04-08 | — | — | US | claimed |