Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670590 | 1.00 | OPRL1 (0.44) | OPRL1GPR119MMP13CYP2D6CYP2C19 | |
| SCHEMBL5669289 | 0.92 | STS (0.44) | GPR119ALDH1A1LMNASTSMC4R | |
| SCHEMBL5669290 | 0.92 | STS (0.44) | GPR119ALDH1A1LMNASTSMC4R | |
| SCHEMBL5671997 | 0.87 | CYP2D6 (0.45) | OPRL1CYP2D6CYP2C19PKMGRM5 | |
| SCHEMBL5671999 | 0.87 | CYP2D6 (0.45) | OPRL1CYP2D6CYP2C19PKMGRM5 | |
| SCHEMBL5671796 | 0.83 | OPRL1 (0.43) | OPRL1CYP2D6CYP2C19ALDH1A1PKM | |
| SCHEMBL5669532 | 0.83 | OPRL1 (0.42) | OPRL1CYP2D6CYP2C19PKMGRM5 | |
| SCHEMBL5670591 | 0.77 | MMP13 (0.42) | OPRL1GPR119MMP13CYP2D6CYP2C19 | |
| SCHEMBL5670593 | 0.77 | MMP13 (0.42) | OPRL1GPR119MMP13CYP2D6CYP2C19 | |
| SCHEMBL4609379 | 0.75 | ADAM10 (0.46) | GPR119MMP13PKMSTSADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276507-A1 | Hydroxamate sulfonamides as cd23 shedding inhibitors | CELLTECH R&D LIMITED (GB) | 2006-12-07 | — | — | US | disclosed |
| EP-1648868-B1 | HYDROXAMATE SULFONAMIDES AS CD23 SHEDDING INHIBITORS | CELLTECH R&D LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276507-A1 | Hydroxamate sulfonamides as cd23 shedding inhibitors | CD2, CD22, NEU3 | OPRL1 1506/4885GPR119 3793/4885MMP13 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.