Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.45 |
| ▸ | CPT1A | P50416 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CRAT | P43155 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11505398 | 0.98 | SLC22A16 (0.52) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Acetic Acid SCHEMBL31405638 | 0.98 | SLC22A16 (0.52) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Acetic Acid SCHEMBL11505402 | 0.98 | SLC22A16 (0.52) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Bicarbonate SCHEMBL28323257 | 0.92 | SLC22A16 (0.56) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Bicarbonate SCHEMBL8320369 | 0.90 | SLC22A16 (0.54) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Acetic Acid SCHEMBL28210362 | 0.87 | MAPT (0.50) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Methacrylic Acid SCHEMBL6678142 | 0.87 | SLC22A16 (0.47) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Carbamic Acid SCHEMBL11505008 | 0.86 | MAPT (0.50) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Carbamic Acid SCHEMBL11505013 | 0.86 | SLC22A16 (0.50) | SLC22A16TSHRCHRM2CHRM4CHRM1 | |
| Propionic Acid SCHEMBL11657756 | 0.86 | SLC22A16 (0.56) | SLC22A16TSHRCHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7063154-B2 | Methods of treating subterranean zones and treating fluids therefor | HALLIBURTON ENERGY SERVICES, INC. (US) | 2006-06-20 | — | — | US | claimed |
| US-20050039918-A1 | Methods of treating subterranean zones and treating fluids therefor | HALLIBURTON ENERGY SERVICES, INC. | 2005-02-24 | — | — | US | claimed |
| EP-0501776-A1 | Stabilization of subterranean formations | HALLIBURTON COMPANY (US) | 1992-09-02 | — | — | EP | claimed |
| US-5097904-A | Flow control agents in enhanced oil recovery | HALLIBURTON COMPANY (US) | 1992-03-24 | — | — | US | claimed |
| EP-0045090-B1 | URETHANE CATALYSIS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-12-04 | — | — | EP | claimed |
| EP-0045090-A1 | Urethane catalysis | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1982-02-03 | — | — | EP | claimed |
| US-4286073-A | Urethane catalysis | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1981-08-25 | — | — | US | claimed |
| CN-110172173-B | Composition for reaction with isocyanate | 红宝丽集团股份有限公司 | 2021-07-09 | — | — | CN | disclosed |
| WO-2020244371-A1 | COMPOSITION USED FOR REACTING WITH ISOCYANATE | 红宝丽集团股份有限公司 | 2020-12-10 | — | — | WO | disclosed |
| CN-111471210-A | Polyurethane composition of pentane co-foaming system and preparation method of polyurethane rigid foam | 南京红宝丽聚氨酯有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-110172173-A | A kind of composition for being reacted with isocyanates | 红宝丽集团股份有限公司 | 2019-08-27 | — | — | CN | disclosed |
| EP-2758487-A1 | MULTI-STAGE METHODS AND COMPOSITIONS FOR DESENSITIZING SUBTERRANEAN FORMATIONS FACES | Halliburton Energy Services, Inc. (US) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013043292-A1 | MULTI-STAGE METHODS AND COMPOSITIONS FOR DESENSITIZING SUBTERRANEAN FORMATIONS FACES | HALLIBURTON ENERGY SERVICES, INC. (US) | 2013-03-28 | — | — | WO | disclosed |
| US-5197544-A | Stimulating hydrocarbon production | HALLIBURTON COMPANY (US) | 1993-03-30 | — | — | US | disclosed |
| EP-0501776-A1 | Stabilization of subterranean formations | HALLIBURTON COMPANY (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5097904-A | Flow control agents in enhanced oil recovery | HALLIBURTON COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0045090-B1 | URETHANE CATALYSIS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1985-12-04 | — | — | EP | disclosed |
| EP-0045090-A1 | Urethane catalysis | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1982-02-03 | — | — | EP | disclosed |
| US-4286073-A | Urethane catalysis | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4101465-A | TO POLYISOCYANURATES, ALKALI METAL GLYCINE SALTS, QUATERNARY AMMONM CARBOXYLATES, ALKALI METAL SALTS OF AMIDES AND ACIDS | THE UPJOHN COMPANY (US) | 1978-07-18 | — | — | US | disclosed |