Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351891 | 0.84 | MEN1 (0.48) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL7195292 | 0.78 | MEN1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3431356 | 0.77 | MEN1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL1082915 | 0.77 | MEN1 (0.69) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5363287 | 0.76 | MEN1 (0.44) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5332900 | 0.75 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6057067 | 0.75 | MCHR1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL8161046 | 0.75 | HTR7 (0.52) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL79979 | 0.75 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL10351892 | 0.75 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7002022-B2 | N-Aryl (thio) anthranilic acid amide derivatives, their preparation and their use as VEGF | NOVARTIS AG (CH) | 2006-02-21 | — | — | US | claimed |
| EP-0064657-A1 | Cyclic sulfenamides, process for their preparation, medicines containing them and preparation of the latter | BAYER AG (DE) | 1982-11-17 | — | — | EP | claimed |
| US-4873333-A | Nitrogen-containing bidentate compound immobilized on a solid inorganic carrier | SHELL OIL COMPANY (US) | 1989-10-10 | — | — | US | disclosed |