SCHEMBL79979

SCHEMBL79979

C=CCSc1ccccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ACHE P22303 3/20 0.39
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 2/20 0.38
EPHX2 P34913 1/20 0.38
HPGD P15428 2/20 0.37
ALOX15 P16050 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
CA12 O43570 1/20 0.36
GMNN O75496 1/20 0.36
EGFR P00533 1/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 1/20 0.36
FYN P06241 1/20 0.36
POLB P06746 1/20 0.36
CA3 P07451 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10351891 0.84 MEN1 (0.48) MEN1KMT2AL3MBTL1MAPK1ALDH1A1
SCHEMBL11198541 0.84 ALDH1A1 (0.37) MEN1KMT2AL3MBTL1ACHEMAPK1
SCHEMBL10639464 0.84 ALDH1A1 (0.41) MEN1KMT2AL3MBTL1ACHEMAPK1
SCHEMBL10430629 0.82 L3MBTL1 (0.34) MEN1KMT2AL3MBTL1ACHEMAPK1
SCHEMBL3262579 0.81 TRPA1 (0.41) MEN1KMT2AL3MBTL1ACHEMAPK1
SCHEMBL11198547 0.81 MAPK1 (0.38) MEN1KMT2AL3MBTL1ACHEMAPK1
SCHEMBL68951 0.80 HSPA5 (0.46) L3MBTL1MAPK1ALDH1A1EPHX2HPGD
SCHEMBL6588281 0.80 MAPK1 (0.37) MEN1KMT2AL3MBTL1ACHEMAPK1
SCHEMBL7195292 0.78 MEN1 (0.43) MEN1KMT2AL3MBTL1MAPK1ALDH1A1
SCHEMBL77637 0.78 MAPT (0.47) MEN1KMT2AL3MBTL1ALDH1A1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102827668-B Synthesis method of high-base-number basic zinc carbonate lubricant additive UNIV HENAN 2013-10-16 CN claimed
CN-102827668-A Synthesis method of high-base-number basic zinc carbonate lubricant additive UNIV HENAN 2012-12-19 CN claimed
EP-0318394-B1 Process for the alkylthiolation of phenols and its application in the synthesis of 4-acyl-2-alkylthiophenols ELF AQUITAINE (FR) 1994-02-02 EP claimed
EP-0203827-B1 PROCESS FOR PREPARING ORTHO-(ALKYLTHIO) PHENOLS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-05 EP claimed
EP-0156352-B1 PREPARATION OF (ALKYLTHIO-,CYCLOALKYTHIO- OR ARYLTHIO)-PHENOLS ETHYL CORPORATION (US) 1988-08-03 EP claimed
EP-0203827-A1 Process for preparing ortho-(alkylthio) phenols E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-03 EP claimed
US-4599451-A PHENOL WITH DIALKYL DISULFIDE, ZIRCONIUM PHENOXIDE CATALYST E. I. DUPONT DE NEMOURS AND COMPANY (US) 1986-07-08 US claimed
US-4547593-A REDISTRIBUTION OF HYDROCARBYLTHIO GROUPS; ALUMINUM PHENOXIDE CATALYST ETHYL CORPORATION (US) 1985-10-15 US claimed
EP-0156352-A2 Preparation of (alkylthio-,cycloalkythio- or arylthio)-phenols ETHYL CORPORATION (US) 1985-10-02 EP claimed
CN-110312782-A Speed reducer lubricant compositions and speed reducer 协同油脂株式会社 2019-10-08 CN disclosed
CN-103717659-B The polymer composition that is filled through and can co-extrusion ejecting plate therefrom 科思创德国股份有限公司 2017-06-23 CN disclosed
CN-105992653-A Multilayer structure made of polycarbonate and polycarbonate blends and having high optical quality, high scratch resistance and weathering strength 科思创德国股份有限公司 2016-10-05 CN disclosed
CN-105837845-A Multi-layer bodies made of polycarbonate with a deep gloss effect 拜耳知识产权有限责任公司 2016-08-10 CN disclosed
CN-103946283-B Multilayer article made of polycarbonate with a dark lustre effect BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-06-01 CN disclosed
EP-0156352-A2 Preparation of (alkylthio-,cycloalkythio- or arylthio)-phenols ETHYL CORPORATION (US) 1985-10-02 EP disclosed
US-4308199-A ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-12-29 US disclosed
US-4042705-A 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-3959487-A Control of mites with polychloro parathio phenols PPG INDUSTRIES, INC. (US) 1976-05-25 US disclosed
US-3850609-A POLYCHLORO PARATHIO PHENOLS AMERICAN CYANAMID COMPANY, A MAINE CORP. 1974-11-26 US disclosed
US-3723538-A POLYCHLORO PARATHIO PHENOLS AMERICAN CYANAMID COMPANY, A MAINE CORP. 1973-03-27 US disclosed