Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 12/20 | 0.47 |
| ▸ | MEF2D | Q14814 | 12/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443384 | 0.82 | MEN1 (0.64) | HTTNPSR1MEN1LMNAHSP90AA1 | |
| SCHEMBL5443382 | 0.82 | MEN1 (0.64) | HTTNPSR1MEN1LMNAHSP90AA1 | |
| SCHEMBL5431348 | 0.81 | HDAC4 (0.60) | HDAC4MEF2DHTTMMP1MMP2 | |
| SCHEMBL5431345 | 0.81 | HDAC4 (0.60) | HDAC4MEF2DHTTMMP1MMP2 | |
| SCHEMBL5441726 | 0.80 | HTT (0.55) | HDAC4MEF2DHTTMMP1MMP2 | |
| SCHEMBL5441723 | 0.80 | HTT (0.55) | HDAC4MEF2DHTTMMP1MMP2 | |
| SCHEMBL5670848 | 0.79 | HDAC4 (0.60) | HDAC4MEF2DHTTNPSR1MMP1 | |
| SCHEMBL5432546 | 0.79 | NAMPT (0.45) | HDAC4MEF2DHTTNPSR1MMP1 | |
| SCHEMBL5432543 | 0.79 | NAMPT (0.45) | HDAC4MEF2DHTTNPSR1MMP1 | |
| SCHEMBL5672084 | 0.78 | HTR2B (0.47) | HDAC4MEF2DNPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |