Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.38 |
| ▸ | MEF2D | Q14814 | 8/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5431353 | 0.81 | HDAC4 (0.53) | HTR2BNPSR1GRIN1GRIN2BKDM4E | |
| SCHEMBL5443386 | 0.80 | P4HB (0.56) | HTR2BNPSR1GRIN1GRIN2BKDM4E | |
| SCHEMBL5670851 | 0.79 | HDAC4 (0.50) | HTR2BNPSR1GRIN1GRIN2BKDM4E | |
| SCHEMBL5672082 | 0.78 | HDAC4 (0.47) | NPSR1PKMHDAC4MEF2D | |
| SCHEMBL5441731 | 0.77 | NFE2L2 (0.52) | HTR2BKDM4EALDH1A1 | |
| SCHEMBL5432549 | 0.76 | HTR2B (0.47) | HTR2BKDM4EALDH1A1PKM | |
| SCHEMBL5432854 | 0.75 | CYP1A2 (0.63) | HTR2BNPSR1GRIN1GRIN2BALDH1A1 | |
| SCHEMBL3111717 | 0.75 | HSD17B3 (0.63) | HTR2BKDM4EALDH1A1PKMSLC9A1 | |
| SCHEMBL5435241 | 0.75 | MAOA (0.51) | HTR2BNPSR1KDM4EALDH1A1SLC9A1 | |
| SCHEMBL5436016 | 0.74 | HTR2B (0.50) | HTR2BNPSR1KDM4EPKMSLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |