Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.60 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17227810 | 0.86 | ALDH1A1 (0.48) | HDAC4MEF2DALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5432543 | 0.85 | NAMPT (0.45) | HDAC4MEF2DALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5432546 | 0.85 | NAMPT (0.45) | HDAC4MEF2DALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5424258 | 0.84 | ALDH1A1 (0.65) | HDAC4MEF2DALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5424265 | 0.84 | ALDH1A1 (0.65) | HDAC4MEF2DALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5425061 | 0.81 | MMP1 (0.60) | HDAC4MEF2DALDH1A1KDM4EHPGD | |
| SCHEMBL5425057 | 0.81 | MMP1 (0.60) | HDAC4MEF2DALDH1A1KDM4EHPGD | |
| SCHEMBL5443382 | 0.81 | MEN1 (0.64) | KDM4EPKMHTTLMNAMAPT | |
| SCHEMBL5443384 | 0.81 | MEN1 (0.64) | KDM4EPKMHTTLMNAMAPT | |
| SCHEMBL5670851 | 0.80 | HDAC4 (0.50) | HDAC4MEF2DALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |