Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16751786 | 0.78 | ALDH1A1 (0.31) | NPSR1ALDH1A1MAPTGAA | |
| SCHEMBL10267453 | 0.77 | NPSR1 (0.32) | TLR8TLR7NPSR1ALDH1A1MAPT | |
| SCHEMBL12341096 | 0.77 | IDO1 (0.34) | TLR8TLR7ALDH1A1MAPTGAA | |
| SCHEMBL17841635 | 0.76 | NR1I2 (0.39) | TLR8NPSR1ALDH1A1MAPT | |
| SCHEMBL10836677 | 0.72 | TLR8 (0.47) | TLR8TLR7ALDH1A1 | |
| SCHEMBL27690701 | 0.72 | KDM4E (0.36) | — | |
| SCHEMBL11916234 | 0.71 | TLR8 (0.43) | TLR8TLR7NPSR1ALDH1A1 | |
| SCHEMBL10267528 | 0.71 | PDE10A (0.41) | NPSR1ALDH1A1MAPTGAA | |
| SCHEMBL77166 | 0.71 | LMNA (0.30) | — | |
| SCHEMBL13663846 | 0.67 | NPSR1 (0.34) | NPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919528-B2 | Antibiotic; bactericides | GLAXOSMITHKLINE LLC (US) | 2011-04-05 | — | — | US | disclosed |
| EP-1730122-A2 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005095357-A2 | PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-13 | — | — | WO | disclosed |