Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434519 | 0.90 | HDAC8 (0.45) | ALDH1A1HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL5434522 | 0.90 | HDAC8 (0.45) | ALDH1A1HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL30071567 | 0.90 | HDAC8 (0.45) | ALDH1A1HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL5430622 | 0.80 | HTT (0.43) | ALDH1A1HDAC8HDAC6HDAC1LMNA | |
| SCHEMBL30071721 | 0.80 | HTT (0.43) | ALDH1A1HDAC8HDAC6HDAC1LMNA | |
| SCHEMBL5430618 | 0.80 | HTT (0.43) | ALDH1A1HDAC8HDAC6HDAC1LMNA | |
| SCHEMBL5670302 | 0.80 | HTT (0.41) | ALDH1A1HDAC8HDAC6HDAC1HDAC3 | |
| Guanidine SCHEMBL27709639 | 0.78 | HTT (0.42) | ALDH1A1HDAC8HDAC6HDAC1LMNA | |
| SCHEMBL30071741 | 0.78 | LMNA (0.55) | ALDH1A1HDAC8HDAC6HDAC1HDAC3 | |
| SCHEMBL5434722 | 0.78 | LMNA (0.55) | ALDH1A1HDAC8HDAC6HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |