Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5434519 | 0.83 | HDAC8 (0.45) | HTTPTGER4PTGER3PTGER2NFE2L2 | |
| SCHEMBL30071567 | 0.83 | HDAC8 (0.45) | HTTPTGER4PTGER3PTGER2NFE2L2 | |
| SCHEMBL5434522 | 0.83 | HDAC8 (0.45) | HTTPTGER4PTGER3PTGER2NFE2L2 | |
| SCHEMBL30071606 | 0.81 | MAOB (0.62) | HTTMAOBNFE2L2BACE1MAOA | |
| SCHEMBL5436428 | 0.81 | MAOB (0.62) | HTTMAOBNFE2L2BACE1MAOA | |
| SCHEMBL5433894 | 0.81 | MAOB (0.62) | HTTMAOBNFE2L2BACE1MAOA | |
| SCHEMBL5672553 | 0.80 | ALDH1A1 (0.42) | HTTPTGER4PTGER3PTGER2NFE2L2 | |
| Guanidine SCHEMBL27709650 | 0.80 | MAOB (0.60) | HTTMAOBNFE2L2BACE1MAOA | |
| SCHEMBL30071662 | 0.79 | RAB9A (0.50) | HTTMAOBNFE2L2HDAC8HDAC6 | |
| SCHEMBL5436269 | 0.79 | RAB9A (0.50) | HTTMAOBNFE2L2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |