Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672551 | 0.90 | VDR (0.39) | VDRHTTNPC1JAK2RAB9A | |
| SCHEMBL5672570 | 0.83 | HTT (0.36) | HTTSMN1; SMN2ABL1POLBHPGD | |
| SCHEMBL5672562 | 0.83 | HTT (0.36) | HTTSMN1; SMN2ABL1POLBHPGD | |
| SCHEMBL5673843 | 0.82 | VDR (0.39) | VDRHTTNPC1JAK2RAB9A | |
| SCHEMBL6181220 | 0.82 | VDR (0.50) | VDRHTTJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL5675494 | 0.78 | VDR (0.38) | VDRTRAP1HSP90B1PYCR1HSP90AA1 | |
| SCHEMBL5673817 | 0.76 | TBXA2R (0.35) | HTTNPC1JAK2RAB9ASMN1; SMN2 | |
| SCHEMBL5673821 | 0.76 | TBXA2R (0.35) | HTTNPC1JAK2RAB9ASMN1; SMN2 | |
| SCHEMBL6181231 | 0.76 | VDR (0.52) | VDRHTTJAK2RAB9ASMN1; SMN2 | |
| SCHEMBL5174047 | 0.76 | VDR (0.41) | VDRRAB9ASMN1; SMN2NPSR1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |