Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669175 | 0.83 | CETP (0.37) | CETPRXFP1MRGPRX4FFAR4L3MBTL1 | |
| SCHEMBL6279005 | 0.83 | CETP (0.37) | CETPRXFP1MRGPRX4FFAR4L3MBTL1 | |
| SCHEMBL7081580 | 0.82 | CETP (0.43) | CETP | |
| SCHEMBL5671318 | 0.81 | CETP (0.45) | CETPMRGPRX4FFAR4PTPRZ1PTPN1 | |
| SCHEMBL6277876 | 0.81 | CETP (0.36) | CETPRXFP1MRGPRX4L3MBTL1ALDH1A1 | |
| SCHEMBL5671027 | 0.79 | LMNA (0.40) | CETPMRGPRX4BRD4LMNAL3MBTL1 | |
| SCHEMBL5670203 | 0.71 | CETP (0.46) | CETPRXFP1FAAH | |
| SCHEMBL6858362 | 0.70 | GAA (0.43) | CETPLMNAMEN1ALDH1A1GAA | |
| SCHEMBL6280295 | 0.69 | ALDH1A1 (0.42) | CETPMRGPRX4FFAR4L3MBTL1ALDH1A1 | |
| SCHEMBL1904496 | 0.69 | ALDH1A1 (0.42) | CETPMRGPRX4FFAR4L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670446-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005030185-A2 | METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION | JAPAN TOBACCO INC. (JP) | 2005-04-07 | — | — | WO | disclosed |