Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | MMP1 | P03956 | 5/20 | 0.57 |
| ▸ | MMP2 | P08253 | 5/20 | 0.57 |
| ▸ | MMP9 | P14780 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689876 | 1.00 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Guanidine SCHEMBL27689909 | 0.95 | HTT (0.60) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL15121428 | 0.90 | HDAC2 (0.66) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL15121430 | 0.90 | HDAC2 (0.66) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL5424488 | 0.83 | HTT (0.56) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL27709605 | 0.83 | EGFR (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL28767423 | 0.83 | HTT (0.47) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL975354 | 0.82 | HDAC2 (0.70) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| Benzene SCHEMBL28260359 | 0.82 | HDAC2 (0.70) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL975355 | 0.82 | HDAC2 (0.70) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |