Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.70 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | EGFR | P00533 | 5/20 | 0.65 |
| ▸ | MMP1 | P03956 | 6/20 | 0.63 |
| ▸ | MMP2 | P08253 | 6/20 | 0.63 |
| ▸ | MMP9 | P14780 | 6/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975354 | 1.00 | HDAC2 (0.70) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| Benzene SCHEMBL28260359 | 1.00 | HDAC2 (0.70) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL7369073 | 0.98 | HDAC2 (0.68) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL30435616 | 0.83 | ALDH1A1 (0.52) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL29060766 | 0.83 | HDAC2 (0.76) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL11704206 | 0.83 | HDAC3 (0.76) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL4029206 | 0.83 | HDAC2 (0.76) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL1325253 | 0.83 | HDAC2 (1.00) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL559917 | 0.83 | HDAC2 (1.00) | HDAC2HDAC3HDAC4HDAC1HDAC8 | |
| SCHEMBL11704209 | 0.83 | HDAC3 (0.76) | HDAC2HDAC3HDAC4HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108041049-A | A kind of compounded pesticides and its preparation method and application | 广东省林业科学研究院 | 2018-05-18 | — | — | CN | claimed |
| CN-104432097-A | Natural enriching substance for relieving physical fatigue | DUAN ZHANE | 2015-03-25 | — | — | CN | claimed |
| EP-1451246-B1 | RUBBER COMPOSITION FOR RUNNING TREAD AND METHOD FOR OBTAINING SAME | MICHELIN & CIE (FR) | 2013-03-06 | — | — | EP | claimed |
| CN-101045697-B | Clausena lansium stone extraction and preparation method thereof | UNIV JINAN | 2010-12-15 | — | — | CN | claimed |
| US-7649042-B2 | Rubber composition for running tread and method for obtaining same | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2010-01-19 | — | — | US | claimed |
| EP-1411045-B1 | Process for production of optically active amino alcohols | YOKOZAWA TOHRU (JP) | 2008-01-16 | — | — | EP | claimed |
| CN-101045697-A | Clausena lansium stone extraction and preparation method thereof | UNIV JINAN (CN) | 2007-10-03 | — | — | CN | claimed |
| US-20050004267-A1 | Rubber composition for tire tread and process for obtaining such | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2005-01-06 | — | — | US | claimed |
| EP-1451246-A1 | RUBBER COMPOSITION FOR RUNNING TREAD AND METHOD FOR OBTAINING SAME | Société de Technologie Michelin (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003046066-A1 | RUBBER COMPOSITION FOR RUNNING TREAD AND METHOD FOR OBTAINING SAME | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2003-06-05 | — | — | WO | claimed |
| EP-1294707-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2003-03-26 | — | — | EP | claimed |
| WO-2001098290-A2 | THIOPHENE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2001-12-27 | — | — | WO | claimed |
| JP-3014559-A | — | — | None | — | — | JP | disclosed |
| US-20250032448-A1 | COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES | KOH, Hwee Ling (SG) | 2025-01-30 | — | — | US | disclosed |
| US-12144797-B2 | Compound for use in the treatment and/or prevention of parasitic mediated diseases | KOH, Hwee Ling (SG) | 2024-11-19 | — | — | US | disclosed |
| CN-113462278-B | Varnish composition, method for producing polyimide resin, and additive | 东京应化工业株式会社 | 2024-06-07 | — | — | CN | disclosed |
| EP-0048165-A1 | Bis-tetrazolemethyl substituted beta-lactam antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4304774-A | Bis-tetrazolmethyl substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| US-4203896-A | WITH MERCURIC ACETATE AND ACETIC ACID, ACIDIC HYDROLYSIS OF N-PROPENYL GROUP | ELI LILLY AND COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4144232-A | Substituted azetidin-2-one antibiotics | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12144797-B2 | Compound for use in the treatment and/or prevention of parasitic mediated diseases | ICMT, ALG3, PFN1 | HDAC2 2746/4885HDAC3 1357/4885HDAC4 3034/4885 |
| US-20250032448-A1 | COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES | EPX, PKD2, MPO | HDAC2 913/4885HDAC3 1023/4885HDAC4 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.