SCHEMBL975354

SCHEMBL975354

CNC(=O)/C=C/c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 3/20 0.70
HDAC3 O15379 2/20 0.70
HDAC4 P56524 2/20 0.70
HDAC1 Q13547 2/20 0.70
HDAC8 Q9BY41 2/20 0.70
HDAC6 Q9UBN7 2/20 0.70
EGFR P00533 5/20 0.65
MMP1 P03956 6/20 0.63
MMP2 P08253 6/20 0.63
MMP9 P14780 6/20 0.63
MAOA P21397 1/20 0.63
MAOB P27338 1/20 0.63
TDP1 Q9NUW8 2/20 0.61
GLA P06280 1/20 0.61
ALDH1A1 P00352 2/20 0.61
KMT2A Q03164 1/20 0.59
TNKS O95271 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC10 Q969S8 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975355 1.00 HDAC2 (0.70) HDAC2HDAC3HDAC4HDAC1HDAC8
Benzene SCHEMBL28260359 1.00 HDAC2 (0.70) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL7369073 0.98 HDAC2 (0.68) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL30435616 0.83 ALDH1A1 (0.52) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL29060766 0.83 HDAC2 (0.76) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL11704206 0.83 HDAC3 (0.76) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL4029206 0.83 HDAC2 (0.76) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL1325253 0.83 HDAC2 (1.00) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL559917 0.83 HDAC2 (1.00) HDAC2HDAC3HDAC4HDAC1HDAC8
SCHEMBL11704209 0.83 HDAC3 (0.76) HDAC2HDAC3HDAC4HDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108041049-A A kind of compounded pesticides and its preparation method and application 广东省林业科学研究院 2018-05-18 CN claimed
CN-104432097-A Natural enriching substance for relieving physical fatigue DUAN ZHANE 2015-03-25 CN claimed
CN-101045697-B Clausena lansium stone extraction and preparation method thereof UNIV JINAN 2010-12-15 CN claimed
CN-101045697-A Clausena lansium stone extraction and preparation method thereof UNIV JINAN (CN) 2007-10-03 CN claimed
US-4226864-A BACTERICIDES, ANTIBIOTICS SHIONOGI & CO., LTD. (JP) 1980-10-07 US claimed
US-20250032448-A1 COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES KOH, Hwee Ling (SG) 2025-01-30 US disclosed
US-12144797-B2 Compound for use in the treatment and/or prevention of parasitic mediated diseases KOH, Hwee Ling (SG) 2024-11-19 US disclosed
CN-113462278-B Varnish composition, method for producing polyimide resin, and additive 东京应化工业株式会社 2024-06-07 CN disclosed
US-20230301984-A1 CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-09-28 US disclosed
US-20230295236-A1 COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS PHARMA MAR, S.A. (ES) 2023-09-21 US disclosed
CN-113462278-A Varnish composition, method for producing polyimide resin, and additive 东京应化工业株式会社 2021-10-01 CN disclosed
US-20210163423-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS NEUPHARMA, INC. 2021-06-03 US disclosed
EP-0406958-B1 Positive inotropic and lusitropic 3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one derivatives JANSSEN PHARMACEUTICA NV (BE) 1995-03-15 EP disclosed
CN-1097417-A New heterogeneous ring compound FUJISAWA PHARMACEUTICAL CO (JP) 1995-01-18 CN disclosed
EP-0623614-A1 4-Aryl-4-hydroxy-tetrahydropyrans and 3-aryl-3-hydroxy-tetrahydrofurans as 5-lipoxygenase inhibitors ZENECA LIMITED (GB) 1994-11-09 EP disclosed
EP-0622361-A1 Heterocyclic compounds as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-11-02 EP disclosed
CN-1089947-A New heterogeneous ring compound FUJISAWA PHARMACEUTICAL CO (JP) 1994-07-27 CN disclosed
EP-0596406-A1 Imidazo (1,2-a) Pyridines as bradykinin antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-05-11 EP disclosed
EP-0406958-A2 Positive inotropic and lusitropic 3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1991-01-09 EP disclosed
US-4226864-A BACTERICIDES, ANTIBIOTICS SHIONOGI & CO., LTD. (JP) 1980-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295236-A1 COMPOUNDS FOR USE IN INFLAMMATORY CONDITIONS TLR4, TLR3, TLR2 HDAC2 753/4885HDAC3 651/4885HDAC4 802/4885
US-20210163423-A1 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS BRAF, PIK3CA, PLK1 HDAC2 808/4885HDAC3 827/4885HDAC4 1128/4885
US-12144797-B2 Compound for use in the treatment and/or prevention of parasitic mediated diseases ICMT, ALG3, PFN1 HDAC2 2746/4885HDAC3 1357/4885HDAC4 3034/4885
US-20230301984-A1 CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION ALDH1A2, PDE6D, PDE6C HDAC2 263/4885HDAC3 243/4885HDAC4 617/4885
US-20250032448-A1 COMPOUND FOR USE IN THE TREATMENT AND/OR PREVENTION OF PARASITIC MEDIATED DISEASES EPX, PKD2, MPO HDAC2 913/4885HDAC3 1023/4885HDAC4 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.