Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 5/20 | 0.50 |
| ▸ | PGK2 | P07205 | 5/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617420 | 0.82 | PGK1 (0.67) | PGK1PGK2ENPP2DGAT2 | |
| SCHEMBL8587479 | 0.79 | SLC6A4 (0.53) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL915395 | 0.76 | NR1H2 (0.54) | PGK1PGK2ENPP2 | |
| SCHEMBL6181124 | 0.76 | SLC6A4 (0.42) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL11304410 | 0.76 | ENPP2 (0.60) | PGK1PGK2ENPP2PLK1DGAT2 | |
| SCHEMBL916486 | 0.76 | PGK1 (0.61) | PGK1PGK2ENPP2DGAT2 | |
| SCHEMBL4620301 | 0.76 | SLC6A4 (0.48) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL9407120 | 0.75 | PGK1 (0.59) | PGK1PGK2ENPP2 | |
| SCHEMBL11481753 | 0.74 | PGK1 (0.59) | PGK1PGK2ENPP2DGAT2 | |
| SCHEMBL916540 | 0.73 | ENPP2 (0.71) | PGK1PGK2ENPP2PLK1DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156877-B2 | 17-hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzylidene derivatives, methods for the production thereof and use thereof for treating diseases | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-13 | — | — | US | disclosed |
| US-20120316145-A1 | 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-BENZYLIDENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-12-13 | — | — | US | disclosed |
| EP-1617420-A2 | Magnetic recording medium | FUJI PHOTO FILM CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-20060008680-A1 | Magnetic recording medium | FUJI PHOTO FILM CO., LTD. | 2006-01-12 | — | — | US | disclosed |
| US-6572986-B2 | Subjecting the phosphor, the organic phosphorus compound, and a polyurethane binder to dispersing processing in order to prepare a coating mixture, applying the coating on a substrate to form phoshor layer | FUJI PHOTO FILM CO., LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| US-20010053461-A1 | Radiation image storage panel and process for producing the same | FUJIFILM CORPORATION (JP) | 2001-12-20 | — | — | US | disclosed |
| US-6099895-A | PHOSPHONIC ACID SURFACE MODIFYING COMPOUND | IMATION CORP. (US) | 2000-08-08 | — | — | US | disclosed |
| US-5868959-A | MAGNETIC PIGMENT HAVING ARALKYL PHOSPHONIC ACID ADSORBED ONTO SURFACE; HIGH SATURATION MAGNETIZATION AND HIGH SURFACE AREA | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5501821-A | OPTICAL ARTICLES FOR TRANSMISSION OF ELECTROMAGNETIC WAVES WITH DIPOLES | EASTMAN KODAK COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316145-A1 | 17-HYDROXY-17-PENTAFLUORETHYL-ESTRA-4,9(10)-DIEN-11-BENZYLIDENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR TREATING DISEASES | HSD17B11, CYP17A1, CYP19A1 | PGK1 3755/4885PGK2 3708/4885ENPP2 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.