Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 18/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.39 |
| ▸ | PTGIR | P43119 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672963 | 1.00 | PTGER3 (0.44) | PTGER3PTGER4PTGER1PTGER2PTGIR | |
| SCHEMBL5674036 | 0.92 | PTGER3 (0.38) | PTGER3PTGER4PTGER1PTGER2PTGIR | |
| SCHEMBL5674032 | 0.92 | PTGER3 (0.38) | PTGER3PTGER4PTGER1PTGER2PTGIR | |
| SCHEMBL5675528 | 0.88 | PTGER3 (0.41) | PTGER3PTGER4 | |
| SCHEMBL5675520 | 0.88 | PTGER3 (0.41) | PTGER3PTGER4 | |
| SCHEMBL5215201 | 0.86 | PTGER3 (0.41) | PTGER3 | |
| SCHEMBL5215186 | 0.86 | PTGER3 (0.41) | PTGER3 | |
| SCHEMBL5675526 | 0.84 | PTGDR2 (0.39) | PTGER3 | |
| SCHEMBL5675517 | 0.84 | PTGDR2 (0.39) | PTGER3 | |
| SCHEMBL5672584 | 0.82 | PPARG (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |