Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 7/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215201 | 1.00 | PTGER3 (0.41) | PTGER3PTGESALOX5BCL2L1MCL1 | |
| SCHEMBL5675520 | 0.96 | PTGER3 (0.41) | PTGER3BCL2L1MCL1 | |
| SCHEMBL5675528 | 0.96 | PTGER3 (0.41) | PTGER3BCL2L1MCL1 | |
| SCHEMBL5673734 | 0.90 | HDAC1 (0.41) | PTGER3LMNA | |
| SCHEMBL5673729 | 0.90 | HDAC1 (0.41) | PTGER3LMNA | |
| SCHEMBL5673019 | 0.88 | PTGER3 (0.38) | PTGER3LMNATASP1 | |
| SCHEMBL5675585 | 0.88 | PTGER3 (0.42) | PTGER3TASP1 | |
| SCHEMBL5217844 | 0.88 | PTGER3 (0.38) | PTGER3LMNATASP1 | |
| SCHEMBL5675592 | 0.88 | PTGER3 (0.42) | PTGER3TASP1 | |
| SCHEMBL5673810 | 0.88 | PTGES (0.45) | PTGER3PTGESALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| EP-1142879-B1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | ASTELLAS PHARMA INC (JP) | 2007-10-10 | — | — | EP | disclosed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |