Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 9/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675528 | 1.00 | PTGER3 (0.41) | PTGER3PTGER4HPGDNPSR1L3MBTL1 | |
| SCHEMBL5215201 | 0.96 | PTGER3 (0.41) | PTGER3BCL2L1MCL1 | |
| SCHEMBL5215186 | 0.96 | PTGER3 (0.41) | PTGER3BCL2L1MCL1 | |
| SCHEMBL6182713 | 0.91 | PTGER3 (0.49) | PTGER3PTGER4HPGDNPSR1L3MBTL1 | |
| SCHEMBL6182705 | 0.91 | PTGER3 (0.49) | PTGER3PTGER4HPGDNPSR1L3MBTL1 | |
| SCHEMBL5675526 | 0.89 | PTGDR2 (0.39) | PTGER3 | |
| SCHEMBL5675517 | 0.89 | PTGDR2 (0.39) | PTGER3 | |
| SCHEMBL5672969 | 0.88 | PTGER3 (0.44) | PTGER3PTGER4 | |
| SCHEMBL5672963 | 0.88 | PTGER3 (0.44) | PTGER3PTGER4 | |
| SCHEMBL5674036 | 0.87 | PTGER3 (0.38) | PTGER3PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |