Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.51 |
| ▸ | PRKX | P51817 | 1/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673045 | 1.00 | S1PR1 (0.51) | S1PR1S1PR5PRKXACVR1PTGER3 | |
| SCHEMBL5675413 | 0.90 | ALDH1A1 (0.41) | S1PR1S1PR5PRKXACVR1PTGER3 | |
| SCHEMBL5675408 | 0.90 | ALDH1A1 (0.41) | S1PR1S1PR5PRKXACVR1PTGER3 | |
| SCHEMBL5673966 | 0.88 | S1PR1 (0.49) | S1PR1S1PR5PRKXACVR1ALDH1A1 | |
| SCHEMBL5674028 | 0.86 | KDM4E (0.39) | S1PR1S1PR5PRKXACVR1ALDH1A1 | |
| SCHEMBL5674030 | 0.86 | KDM4E (0.39) | S1PR1S1PR5PRKXACVR1ALDH1A1 | |
| SCHEMBL5673719 | 0.85 | S1PR1 (0.43) | S1PR1S1PR5PRKXACVR1PTGER3 | |
| SCHEMBL5672554 | 0.85 | S1PR1 (0.43) | S1PR1S1PR5PRKXACVR1PTGER3 | |
| SCHEMBL5673725 | 0.85 | S1PR1 (0.43) | S1PR1S1PR5PRKXACVR1PTGER3 | |
| SCHEMBL5672552 | 0.85 | S1PR1 (0.43) | S1PR1S1PR5PRKXACVR1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |