Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | PRKX | P51817 | 1/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675408 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL5673045 | 0.90 | S1PR1 (0.51) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL5673053 | 0.90 | S1PR1 (0.51) | ALDH1A1KDM4EPKMPTGER3PTGDR | |
| SCHEMBL5673931 | 0.88 | ALDH1A1 (0.42) | ALDH1A1S1PR1S1PR5PRKXACVR1 | |
| SCHEMBL5675529 | 0.85 | BCL2L1 (0.42) | PTGER3 | |
| SCHEMBL5673798 | 0.85 | APP (0.40) | PTGER3PTGDR2PTGER1PTGER4PTGER2 | |
| SCHEMBL5675522 | 0.85 | BCL2L1 (0.42) | PTGER3 | |
| SCHEMBL5673791 | 0.85 | APP (0.40) | PTGER3PTGDR2PTGER1PTGER4PTGER2 | |
| SCHEMBL5673807 | 0.83 | HDAC1 (0.41) | ALDH1A1KDM4EPTGER3PTGDRPTGDR2 | |
| SCHEMBL5673799 | 0.83 | HDAC1 (0.41) | ALDH1A1KDM4EPTGER3PTGDRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |