Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634701 | 0.93 | MAPT (0.47) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL5672743 | 0.91 | PTGDR2 (0.43) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL4634373 | 0.90 | CCR1 (0.53) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL4635008 | 0.90 | PTGDR2 (0.44) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL4634705 | 0.90 | PTGDR2 (0.44) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL4634943 | 0.89 | PTGDR2 (0.45) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL4634628 | 0.89 | CCR1 (0.55) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL4634679 | 0.88 | CCR1 (0.46) | PTGDR2HTTCCR1SMN1; SMN2TSHR | |
| SCHEMBL4635597 | 0.87 | PTGDR2 (0.45) | PTGDR2HTTSMN1; SMN2TSHRGAA | |
| SCHEMBL4633976 | 0.87 | LMNA (0.53) | HTTCCR1SMN1; SMN2TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167044-A1 | Piperidine derivatives and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167044-A1 | Piperidine derivatives and their use as anti-inflammatory agents | CCR1, CCR2, CCR3 | PTGDR2 75/4885HTT 4424/4885CCR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.