SCHEMBL5674151

SCHEMBL5674151

Cc1ncc([C]=O)c(Cl)n1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
MAPT P10636 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 2/20 0.31
NTRK1 P04629 1/20 0.30
PDK2 Q15119 1/20 0.30
PDK4 Q16654 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12726137 0.79 CSNK1A1 (0.46) CYP1A2CYP2C9CYP2C19L3MBTL1TDP1
SCHEMBL3595385 0.78 CSNK1A1 (0.44)
SCHEMBL2896218 0.75
SCHEMBL5677074 0.71 CSNK1A1 (0.41)
SCHEMBL12476433 0.71 MAPT (0.41) CYP1A2MAPTCYP2C9CYP2C19L3MBTL1
SCHEMBL5677422 0.71 TP53 (0.40) MAPTHTTKMT2ANPSR1
SCHEMBL850260 0.70
SCHEMBL3712628 0.70
SCHEMBL14855312 0.68 CCR1 (0.36) CYP1A2MAPTCYP2C9CYP2C19L3MBTL1
SCHEMBL3705875 0.68 LMNA (0.40) CYP1A2MAPTCYP2C9CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060107869-A1 Inks for digital textile printing with reactive yellow fluorescent dyes DYSTAR TEXTILF DEUTSCHLAND KG (DE) 2006-05-25 US disclosed
EP-1646748-A2 INKS FOR DIGITAL TEXTILE PRINTING WITH REACTIVE YELLOW FLUORESCENT DYES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2006-04-19 EP disclosed
EP-1328588-B1 METAL COMPLEX COLOURING AGENTS BASED ON BUCHERER NAPHTHOLS DYSTAR TEXTILFARBEN GMBH & CO (DE) 2006-01-11 EP disclosed
WO-2005005553-A2 INKS FOR DIGITAL TEXTILE PRINTING WITH REACTIVE YELLOW FLUORESCENT DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-01-20 WO disclosed
US-6809187-B2 FIBER REACTIVE COPPER, COBALT OR CHROMIUM CHELATES; LIGHT-FASTNESS; EFFICIENT UNFIXED MATERIAL WASHOFF OYSTAR TEXTIL FARBEN GMBH & CO. (DE) 2004-10-26 US disclosed
US-20040054154-A1 Metal complex dyes based bucherered naphthols DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2004-03-18 US disclosed
EP-1328588-A1 METAL COMPLEX COLOURING AGENTS BASED ON BUCHERER NAPHTHOLS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2003-07-23 EP disclosed
WO-2002033006-A1 METAL COMPLEX COLOURING AGENTS BASED ON BUCHERER NAPHTHOLS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-25 WO disclosed
EP-0748850-B1 Dyestuffs, process for their preparation and their use CIBA SC HOLDING AG (CH) 2001-07-04 EP disclosed
EP-0828870-B1 SPIN DYEING PROCESS WITH DYEING SALTS DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-02-14 EP disclosed
US-4122079-A Reactive azo dyestuffs from diazotized sulfo-amino naphthalenes and diaminosulfobenzenes BAYER AKTIENGESELLSCHAFT (DE) 1978-10-24 US disclosed
US-4118382-A DYES FOR CELLULOSE, WOOL, SILK, POLYAMIDE, AND POLYURETHANE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-4089895-A COUPLER FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1978-05-16 US disclosed
US-4072463-A MONOAZO AND DISAZO DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DT) 1978-02-07 US disclosed
US-4065446-A Reactive dyestuffs containing urea alkylene linkage between chromophore and reactive radical BAYER AKTIENGESELLSCHAFT (DT) 1977-12-27 US disclosed
US-4051134-A Reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed
US-4049704-A AZO REACTIVE DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-09-20 US disclosed
US-3989692-A PHTHALOCYANINE DYES, WOOL, SILK, POLYAMIDES, CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed
US-3988310-A FIBER-REACTIVE DYES; CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed
US-3957751-A WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060107869-A1 Inks for digital textile printing with reactive yellow fluorescent dyes IK, COL1A1, DDX41 CYP1A2 181/4885MAPT 1168/4885CYP2C9 654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.