Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674238 | 0.85 | CYP1A2 (0.48) | EPHX2MEN1KMT2AUSP2CTSB | |
| SCHEMBL5142124 | 0.83 | HPGD (0.56) | EPHX2KMT2AEPHX1HPGDSTS | |
| SCHEMBL5674894 | 0.82 | MAPT (0.51) | MEN1KMT2AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7533918 | 0.81 | CTSB (0.40) | EPHX2MEN1KMT2ACTSBCTSS | |
| SCHEMBL17684002 | 0.80 | EPHX1 (0.47) | EPHX2EPHX1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL5675372 | 0.79 | EPHX2 (0.47) | EPHX2KMT2AMAPTSMN1; SMN2CTSB | |
| SCHEMBL5674323 | 0.79 | EPHX2 (0.47) | EPHX2MEN1KMT2AEPHX1SMN1; SMN2 | |
| SCHEMBL5674901 | 0.79 | MEN1 (0.47) | EPHX2MEN1KMT2AMAPTSTS | |
| SCHEMBL1840770 | 0.78 | CTSB (0.47) | MEN1KMT2ASMN1; SMN2CTSBCTSS | |
| SCHEMBL1840796 | 0.78 | CTSB (0.47) | MEN1KMT2ASMN1; SMN2CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | claimed |
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-1619189-B1 | N-(3-acyl-2-hydroxyalkyl) cycloalkyl amide derivatives | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| US-7109275-B2 | Co-metering of organic initiators and protective colloids during polymerization reactions | AKZO NOBEL N.V. (NL) | 2006-09-19 | — | — | US | disclosed |
| EP-1495057-B1 | CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS | AKZO NOBEL NV (NL) | 2006-08-02 | — | — | EP | disclosed |
| EP-1008592-B1 | Cyclic amide derivatives which inhibit cathepsin K | SEIKAGAKU KOGYO CO LTD (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1008592-B1 | Cyclic amide derivatives which inhibit cathepsin K | SEIKAGAKU KOGYO CO LTD (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1619189-A1 | N-(3-acyl-2-hydroxyalkyl) cycloalkyl amide derivatives | SEIKAGAKU CORPORATION (JP) | 2006-01-25 | — | — | EP | disclosed |
| EP-1616867-A1 | Hydroxycarboxylic acid derivatives | SEIKAGAKU CORPORATION (JP) | 2006-01-18 | — | — | EP | disclosed |
| EP-1616859-A1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU CORPORATION (JP) | 2006-01-18 | — | — | EP | disclosed |
| EP-1495057-A1 | CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS | Akzo Nobel N.V. (NL) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087168-A1 | CO-METERING OF ORGANIC INITIATORS AND PROTECTIVE COLLOIDS DURING POLYMERIZATION REACTIONS | AKZO NOBEL N.V. (NL) | 2003-10-23 | — | — | WO | disclosed |
| US-20030199656-A1 | Co-metering of organic initiators and protective colloids during polymerization reactions | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2003-10-23 | — | — | US | disclosed |
| US-6117870-A | USEFUL AS THERAPEUTIC DRUG OR PREVENTIVE DRUG OF ARTHRITIS AND RHEUMATISM DUE TO INCREASE OF BONE RESORPTION IN ADDITION TO BONE DISEASES SUCH AS OSTEOPOROSIS, HYPERCALCEMIA, AND PAGET'S DISEASE | FUJIREBIO KABUSHIKI KAISHA (JP) | 2000-09-12 | — | — | US | disclosed |
| EP-1008592-A2 | Cyclic amide derivatives which inhibit cathepsin K | Fujirebio Kabushiki Kaisha (JP) | 2000-06-14 | — | — | EP | disclosed |