SCHEMBL7533918

SCHEMBL7533918

CC(C)(C)N1CCN(C(=O)NC2(C(=O)O)CCCCC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSB P07858 4/20 0.40
CTSS P25774 4/20 0.40
CTSK P43235 2/20 0.40
CTSL P07711 2/20 0.36
EPHX2 P34913 3/20 0.33
HRH3 Q9Y5N1 1/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
CNR2 P34972 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5675372 0.83 EPHX2 (0.47) CTSBCTSSCTSKEPHX2ALDH1A1
SCHEMBL5674323 0.83 EPHX2 (0.47) CTSBCTSSCTSKEPHX2ALDH1A1
SCHEMBL1840796 0.82 CTSB (0.47) CTSBCTSSCTSKALDH1A1MEN1
SCHEMBL1840770 0.82 CTSB (0.47) CTSBCTSSCTSKALDH1A1MEN1
SCHEMBL5674155 0.81 EPHX2 (0.54) CTSBCTSSCTSKEPHX2MEN1
SCHEMBL5674238 0.80 CYP1A2 (0.48) CTSBCTSSCTSKEPHX2ALDH1A1
SCHEMBL5674494 0.79 CTSK (0.40) CTSBCTSSCTSKEPHX2ALDH1A1
SCHEMBL5675842 0.78 LMNA (0.52) CTSBCTSSCTSKALDH1A1POLB
SCHEMBL5674894 0.77 MAPT (0.51) ALDH1A1POLBMEN1KMT2AKDM4E
SCHEMBL5677871 0.76 EPHX2 (0.47) CTSBCTSSCTSKCTSLEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002023784-A2 CYSTEINE PROTEASE INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2002-03-21 WO disclosed