⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5574550 | 0.79 | MEN1 (0.31) | — | |
| SCHEMBL14320681 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL2477058 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL2474237 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL1003610 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL20357790 | 0.73 | LMNA (0.35) | — | |
| SCHEMBL2993042 | 0.73 | — | — | |
| SCHEMBL20357691 | 0.73 | MEN1 (0.31) | — | |
| SCHEMBL10819605 | 0.73 | — | — | |
| SCHEMBL20774152 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1653996-A2 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | Novo Nordisk Health Care AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005014035-A2 | USE OF GALACTOSE OXIDASE FOR SELECTIVE CHEMICAL CONJUGATION OF PROTRACTOR MOLECULES TO PROTEINS OF THERAPEUTIC INTEREST | NOVO NORDISK HEALTH CARE AG (CH) | 2005-02-17 | — | — | WO | disclosed |