Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | STS | P08842 | 10/20 | 0.68 |
| ▸ | CA1 | P00915 | 3/20 | 0.68 |
| ▸ | CA2 | P00918 | 3/20 | 0.68 |
| ▸ | CA9 | Q16790 | 3/20 | 0.68 |
| ▸ | ESR1 | P03372 | 2/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.66 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153062 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL8145682 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL8152986 | 0.95 | KDM4E (0.69) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL8144769 | 0.94 | KDM4E (0.68) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL8153960 | 0.93 | KDM4E (0.67) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL8152475 | 0.93 | KDM4E (0.67) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL5676213 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL8144721 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL8153756 | 0.90 | KDM4E (0.68) | KDM4EALDH1A1HSD17B1LMNAMAPT | |
| SCHEMBL14044784 | 0.89 | HSD17B1 (0.74) | KDM4EALDH1A1HSD17B1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169336-B1 | ENT-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | SCHERING AG (DE) | 2006-02-01 | — | — | EP | claimed |
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | claimed |
| EP-1169336-B1 | ENT-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | SCHERING AG (DE) | 2006-02-01 | — | — | EP | disclosed |
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | disclosed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | disclosed |