Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | STS | P08842 | 9/20 | 0.70 |
| ▸ | CA1 | P00915 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | ESR1 | P03372 | 2/20 | 0.69 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.69 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.69 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.69 |
| ▸ | CA4 | P22748 | 1/20 | 0.69 |
| ▸ | CA6 | P23280 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672003 | 1.00 | HSD17B1 (0.74) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL6691697 | 0.96 | HSD17B1 (0.74) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL10134113 | 0.96 | HSD17B1 (0.74) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL7755033 | 0.92 | HSD17B1 (0.74) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL11671118 | 0.91 | HSD17B1 (0.78) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL5527434 | 0.91 | HSD17B1 (0.78) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL6694124 | 0.91 | KDM4E (0.71) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL6696320 | 0.91 | HSD17B1 (0.77) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL9633204 | 0.90 | KDM4E (0.75) | HSD17B1KDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL14377634 | 0.90 | KDM4E (0.72) | HSD17B1KDM4ELMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382288-B2 | Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2016-07-05 | — | — | US | disclosed |
| EP-2013221-B1 | COMPOSITIONS AND METHODS FOR CELLULAR IMAGING AND THERAPY | UNIV TEXAS (US) | 2015-06-24 | — | — | EP | disclosed |
| US-8758723-B2 | Compositions and methods for cellular imaging and therapy | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-06-24 | — | — | US | disclosed |
| US-8758723-B2 | Compositions and methods for cellular imaging and therapy | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-06-24 | — | — | US | disclosed |
| US-20130266645-A1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2013-10-10 | — | — | US | disclosed |
| WO-2008130439-A1 | COMPOSITIONS AND METHODS FOR CELLULAR IMAGING AND THERAPY | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-2007120153-A1 | COMPOSITIONS AND METHODS FOR CELLULAR IMAGING AND THERAPY | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070248537-A1 | Compositions and Methods for Cellular Imaging and Therapy | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2007-10-25 | — | — | US | disclosed |
| US-20070248537-A1 | Compositions and Methods for Cellular Imaging and Therapy | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130266645-A1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | HSD17B7, CYP21A2, CYP17A1 | HSD17B1 12/4885KDM4E 1866/4885LMNA 681/4885 |
| US-20070248537-A1 | Compositions and Methods for Cellular Imaging and Therapy | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NCL, NME4 | HSD17B1 4780/4885KDM4E 3676/4885LMNA 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.