Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 17/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675585 | 1.00 | PTGER3 (0.42) | PTGER3PTGER1PTGER4TYMPPTGFR | |
| SCHEMBL5215201 | 0.88 | PTGER3 (0.41) | PTGER3TASP1 | |
| SCHEMBL5215186 | 0.88 | PTGER3 (0.41) | PTGER3TASP1 | |
| SCHEMBL5673747 | 0.86 | PTGER3 (0.40) | PTGER3PTGER1PTGER4TYMPPTGFR | |
| SCHEMBL5673738 | 0.86 | PTGER3 (0.40) | PTGER3PTGER1PTGER4TYMPPTGFR | |
| SCHEMBL5673744 | 0.86 | PTGER3 (0.40) | PTGER3PTGER1PTGER4TYMPPTGFR | |
| SCHEMBL5673019 | 0.84 | PTGER3 (0.38) | PTGER3TASP1 | |
| SCHEMBL5217844 | 0.84 | PTGER3 (0.38) | PTGER3TASP1 | |
| SCHEMBL5673903 | 0.84 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5673900 | 0.84 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | claimed |
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |