Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6303672 | 0.85 | MAOB (0.48) | MAOBAPPF10FFAR1MAPT | |
| SCHEMBL695003 | 0.84 | S1PR1 (0.57) | MAOBCYP4F2CYP4A11LTA4HEPHX2 | |
| SCHEMBL4796227 | 0.81 | NPC1 (0.60) | MAOBAPPPTGDR2FFAR1MAPT | |
| SCHEMBL5673944 | 0.77 | MAOB (0.42) | MAOBAPPFFAR1SMN1; SMN2NPC1 | |
| SCHEMBL23667705 | 0.76 | TSHR (0.41) | MAPTSMN1; SMN2NPC1TP53XBP1 | |
| SCHEMBL11128958 | 0.75 | APP (0.50) | MAOBAPPF10FFAR1CYP4F2 | |
| SCHEMBL11854931 | 0.75 | MAOB (0.54) | MAOBPTGDR2FFAR1MAPTNPC1 | |
| Phenoxyethanol SCHEMBL28902090 | 0.75 | ALDH1A1 (0.58) | FFAR1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5400014 | 0.75 | APP (0.64) | MAOBAPPFFAR1CYP4F2CYP4A11 | |
| SCHEMBL2987086 | 0.75 | ALOX5 (0.51) | MAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |