Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL57027 | 0.97 | USP2 (0.31) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL2843635 | 0.97 | — | — | |
| SCHEMBL16190500 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL18300165 | 0.90 | — | — | |
| SCHEMBL15497075 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL15511141 | 0.83 | — | — | |
| SCHEMBL10080813 | 0.78 | P2RX7 (0.33) | P2RX7 | |
| Hydrochloric Acid SCHEMBL360162 | 0.77 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL10062257 | 0.76 | — | — | |
| SCHEMBL14999464 | 0.76 | USP2 (0.33) | USP2ALDH1A1LMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556117-B2 | Indole carboxamide derivatives as P2X7 receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2017-01-31 | — | — | US | claimed |
| EP-2935211-B1 | INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-11-09 | — | — | EP | claimed |
| US-20150344425-A1 | INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-12-03 | — | — | US | claimed |
| EP-4200352-B1 | METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | COVESTRO DEUTSCHLAND AG (DE) | 2025-11-19 | — | — | EP | disclosed |
| EP-4448605-B1 | PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | COVESTRO DEUTSCHLAND AG (DE) | 2025-11-19 | — | — | EP | disclosed |
| EP-4200353-B1 | METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | COVESTRO DEUTSCHLAND AG (DE) | 2025-11-19 | — | — | EP | disclosed |
| EP-4200351-B1 | METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | COVESTRO DEUTSCHLAND AG (DE) | 2025-11-19 | — | — | EP | disclosed |
| US-12466913-B2 | Method for the production of a thermoplastic polyoxazolidinone | COVESTRO DEUTSCHLAND AG (DE) | 2025-11-11 | — | — | US | disclosed |
| US-12378348-B2 | Method for the production of a thermoplastic polyoxazolidinone | COVESTRO DEUTSCHLAND AG (DE) | 2025-08-05 | — | — | US | disclosed |
| US-20250043061-A1 | PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | COVESTRO DEUTSCHLAND AG (DE) | 2025-02-06 | — | — | US | disclosed |
| EP-4448605-A1 | PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | Covestro Deutschland AG (DE) | 2024-10-23 | — | — | EP | disclosed |
| US-5973076-A | MOLDING; CONTROLLING TEMPERATURE IN PRESENCE OF AN AMIDE COMPOUND | NEW JAPAN CHEMICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0776933-B1 | Polybutene-1 resin composition and a method of accelerating the crystal transformation | NEW JAPAN CHEM CO LTD (JP) | 1999-08-04 | — | — | EP | disclosed |
| EP-0589446-B1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BOEHRINGER INGELHEIM CA LTD (CA) | 1997-09-03 | — | — | EP | disclosed |
| EP-0776933-A1 | Polybutene-1 resin composition and a method of accelerating the crystal transformation | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5565476-A | RENIN INHIBITORS FOR TREATMENT OF CONGESTIVE HEART FAILURE AND HYPERTENSION | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-10-15 | — | — | US | disclosed |
| US-5554634-A | HYPOTENSIVE | BIO-MEGA BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-09-10 | — | — | US | disclosed |
| US-5523315-A | N-(hydroxyethyl)butanediamide derivatives | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1996-06-04 | — | — | US | disclosed |
| WO-1994007845-A1 | N-(HYDROXYETHYL)BUTANEDIAMIDE DERIVATIVES AS RENIN INHIBITORS | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-04-14 | — | — | WO | disclosed |
| EP-0589446-A1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344425-A1 | INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | P2RX7, P2RX3, P2RX1 | USP2 4164/4885ALDH1A1 2019/4885LMNA 2785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.