Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | PRCP | P42785 | 8/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920424 | 0.81 | MC4R (0.54) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| SCHEMBL12533727 | 0.81 | MC4R (0.54) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| SCHEMBL29327388 | 0.81 | MC4R (0.54) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| SCHEMBL1921102 | 0.81 | MC4R (0.54) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| SCHEMBL29904543 | 0.80 | MC4R (0.56) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| SCHEMBL3170784 | 0.80 | MC4R (0.56) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| SCHEMBL3160522 | 0.80 | MC4R (0.56) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| Hydrochloric Acid SCHEMBL14991520 | 0.79 | MC4R (0.55) | MC4RKCNH2PRCPMTNR1BHTR2C | |
| Hydrochloric Acid SCHEMBL1920434 | 0.76 | MC4R (0.51) | MC4RKCNH2 | |
| SCHEMBL18914539 | 0.73 | MC1R (0.48) | MC4RKCNH2PRCPMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615882-A2 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYRROLIDINE CARBOXYLIC ACIDS | Merck & Co., Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004092126-A2 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYRROLIDINE CARBOXYLIC ACIDS | MERCK & CO., INC. (US) | 2004-10-28 | — | — | WO | disclosed |