Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.61 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264131 | 0.89 | KIF11 (0.74) | KIF11KCNN4TAAR1MEN1KMT2A | |
| SCHEMBL29679194 | 0.82 | KIF11 (0.65) | KIF11KCNN4MEN1KMT2ADUT | |
| SCHEMBL20823126 | 0.81 | KIF11 (0.50) | KIF11KCNN4TAAR1ATMHTR2A | |
| SCHEMBL1133053 | 0.81 | TAAR1 (0.43) | KIF11KCNN4TAAR1ATMHTR2A | |
| SCHEMBL8961063 | 0.80 | KCNN4 (0.68) | KIF11KCNN4TAAR1KMT2AL3MBTL1 | |
| SCHEMBL10071078 | 0.80 | KIF11 (0.49) | KIF11KCNN4TAAR1ATMHTR2A | |
| SCHEMBL12264133 | 0.79 | KIF11 (0.68) | KIF11KCNN4TAAR1DUTSIGMAR1 | |
| SCHEMBL15577798 | 0.79 | KCNN4 (0.67) | KIF11KCNN4TAAR1HTR2AHTR1B | |
| SCHEMBL14340670 | 0.79 | KCNN4 (0.65) | KIF11KCNN4TAAR1DUTALDH1A1 | |
| SCHEMBL147990 | 0.77 | KIF11 (0.65) | KIF11KCNN4MEN1KMT2ADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| EP-1556035-A4 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECH INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1556035-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026264-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | KIF11 1411/4885KCNN4 4277/4885TAAR1 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.