Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.67 |
| ▸ | KIF11 | P52732 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29679194 | 0.87 | KIF11 (0.65) | KCNN4KIF11DUTMEN1KMT2A | |
| SCHEMBL12264131 | 0.85 | KIF11 (0.74) | KCNN4KIF11DUTMEN1KMT2A | |
| SCHEMBL8961063 | 0.81 | KCNN4 (0.68) | KCNN4KIF11HTTDUTKMT2A | |
| SCHEMBL2490805 | 0.81 | KCNN4 (1.00) | KCNN4KIF11DUTTAAR1 | |
| SCHEMBL6251086 | 0.80 | KIF11 (0.57) | KCNN4KIF11DUT | |
| SCHEMBL5675883 | 0.79 | KIF11 (0.61) | KCNN4KIF11HTTDUTMEN1 | |
| SCHEMBL9617559 | 0.78 | KIF11 (0.78) | KCNN4KIF11DUTMEN1KMT2A | |
| SCHEMBL3626482 | 0.78 | MEN1 (0.65) | KCNN4KIF11MEN1KMT2ATDP1 | |
| SCHEMBL14288491 | 0.78 | KCNN4 (0.63) | KCNN4KIF11HTTDUTLMNA | |
| SCHEMBL12264133 | 0.76 | KIF11 (0.68) | KCNN4KIF11DUTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895457-B1 | OLIGOMER-CONTAINING BENZAMIDE-BASED COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2020-05-20 | — | — | EP | disclosed |
| US-10434181-B2 | Oligomer-containing benzamide-based compounds | NEKTAR THERAPEUTICS (US) | 2019-10-08 | — | — | US | disclosed |
| US-20180185499-A1 | OLIGOMER-CONTAINING BENZAMIDE-BASED COMPOUNDS | NEKTAR THERAPEUTICS | 2018-07-05 | — | — | US | disclosed |
| US-9937266-B2 | Oligomer-containing benzamide-based compounds | NEKTAR THERAPEUTICS (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160339108-A1 | OLIGOMER-CONTAINING BENZAMIDE-BASED COMPOUNDS | NEKTAR THERAPEUTICS | 2016-11-24 | — | — | US | disclosed |
| US-9375486-B2 | Oligomer-containing benzamide-based compounds | NEKTAR THERAPEUTICS (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150250894-A1 | Oligomer-Containing Benzamide-Based Compounds | NEKTAR THERAPEUTICS (US) | 2015-09-10 | — | — | US | disclosed |
| EP-2895457-A1 | OLIGOMER-CONTAINING BENZAMIDE-BASED COMPOUNDS | Nektar Therapeutics (US) | 2015-07-22 | — | — | EP | disclosed |
| WO-2014043707-A1 | OLIGOMER-CONTAINING BENZAMIDE-BASED COMPOUNDS | NEKTAR THERAPEUTICS (US) | 2014-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10434181-B2 | Oligomer-containing benzamide-based compounds | BRDT, BIRC5, BRD8 | KCNN4 1400/4885KIF11 2521/4885HTT 15/4885 |
| US-20160339108-A1 | OLIGOMER-CONTAINING BENZAMIDE-BASED COMPOUNDS | BRDT, BIRC5, BRD8 | KCNN4 1400/4885KIF11 2521/4885HTT 15/4885 |
| US-20150250894-A1 | Oligomer-Containing Benzamide-Based Compounds | BIRC5, BRDT, TBCB | KCNN4 1448/4885KIF11 2566/4885HTT 15/4885 |
| US-20180185499-A1 | OLIGOMER-CONTAINING BENZAMIDE-BASED COMPOUNDS | BRDT, BIRC5, BRD8 | KCNN4 1400/4885KIF11 2521/4885HTT 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.