SCHEMBL5676264

SCHEMBL5676264

CCCCCc1cc(O)c(O)c(C(=O)OCC)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
KDM4E B2RXH2 1/20 0.46
NOD2 Q9HC29 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
ESR1 P03372 2/20 0.44
AKR1C4 P17516 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
AKR1C1 Q04828 1/20 0.44
CYP3A4 P08684 2/20 0.44
TYR P14679 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
USP2 O75604 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5193720 0.84 BID (0.54) KDM4ETYRPTGESTOP2APTPN1
SCHEMBL11316813 0.81 PTGES (0.55) NR1H2NR1H3KDM4ENOD2CYP3A4
SCHEMBL19680127 0.81 NR1H2 (0.45) NR1H2NR1H3KDM4ENOD2CA12
SCHEMBL5590530 0.79 BID (0.48) KDM4EPTGESTOP2APTPN1
SCHEMBL8750720 0.78 PTGES (0.66) NR1H2NR1H3KDM4ENOD2CA12
SCHEMBL29979434 0.78 PTGES (0.66) NR1H2NR1H3KDM4ENOD2CA12
SCHEMBL28646839 0.77 NR1H2 (0.59) NR1H2NR1H3KDM4ENOD2CA12
SCHEMBL8402307 0.77 PTPN1 (0.66) NR1H2NR1H3KDM4ENOD2CYP3A4
SCHEMBL8400549 0.77 PTPN1 (0.66) NR1H2NR1H3KDM4ENOD2CYP3A4
SCHEMBL5681264 0.76 TYR (0.56) CYP3A4TYRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620447-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III Exxonmobil Chemical Patents Inc. (US) 2006-02-01 EP disclosed
WO-2003102006-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-12-11 WO disclosed