Pyrene

Pyrene

SCHEMBL5677014

c1cc2ccc3cccc4ccc(c1)c2c34.c1ccc2c(c1)-c1cccc3cccc-2c13

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.88
HSD17B10 Q99714 8/20 0.88
TSHR P16473 6/20 0.88
MAPK1 P28482 4/20 0.88
L3MBTL1 Q9Y468 3/20 0.88
ATM Q13315 2/20 0.88
HPGD P15428 5/20 0.67
CASP1 P29466 3/20 0.67
CASP7 P55210 2/20 0.67
HIF1A Q16665 2/20 0.67
TP53 P04637 1/20 0.67
CYP3A4 P08684 4/20 0.65
PABPC1 P11940 2/20 0.65
DNMT1 P26358 2/20 0.65
CYP1A2 P05177 3/20 0.65
CYP1A1 P04798 1/20 0.65
CYP1B1 Q16678 1/20 0.65
CES2 O00748 1/20 0.55
BCHE P06276 1/20 0.55
CES1 P23141 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoranthene SCHEMBL8873541 0.94 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Fluoranthene SCHEMBL29355720 0.94 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Fluoranthene SCHEMBL27152 0.94 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Fluoranthene SCHEMBL29396242 0.94 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Pyrene SCHEMBL27726523 0.94 ALDH1A1 (0.77) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
SCHEMBL23525587 0.94 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Pyrene SCHEMBL27541102 0.92 ALDH1A1 (0.75) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Fluoranthene SCHEMBL21326204 0.91 ALDH1A1 (0.94) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Fluoranthene SCHEMBL30911873 0.91 ALDH1A1 (0.94) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1
Fluoranthene SCHEMBL29000576 0.91 ALDH1A1 (0.94) ALDH1A1HSD17B10TSHRMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114307215-B Pyrene rectifying device and pyrene rectifying method 新奥科技发展有限公司 2023-09-08 CN disclosed
CN-114307215-A Pyrene rectification device and pyrene rectification method 新奥科技发展有限公司 2022-04-12 CN disclosed
CN-106645444-B A kind of method of multiring aromatic hydrocarbon substance content in detection smoke-free tobacco product 云南省烟草质量监督检测站 2019-06-04 CN disclosed
EP-1622998-A2 DETERMINATION OF AROMATIC HYDROCARBONS IN EDIBLE OIL PRODUCTS Cargill, Incorporated (US) 2006-02-08 EP disclosed
WO-2004102181-A2 DETERMINATION OF AROMATIC HYDROCARBONS IN EDIBLE OIL PRODUCTS CARGILL, INCORPORATED (US) 2004-11-25 WO disclosed
US-4187369-A Process for producing hydrocarbon-phenol-formaldehyde resin FARBSHTEIN JURY G (SU) 1980-02-05 US disclosed