Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199934 | 0.78 | TSHR (0.33) | TSHR | |
| SCHEMBL10922421 | 0.75 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL645146 | 0.75 | CYP19A1 (0.36) | — | |
| SCHEMBL18547473 | 0.73 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL9052834 | 0.73 | CYP19A1 (0.33) | — | |
| SCHEMBL9123239 | 0.73 | CTSK (0.33) | — | |
| SCHEMBL383938 | 0.72 | CYP2C19 (0.35) | — | |
| SCHEMBL16086439 | 0.72 | TSHR (0.39) | TSHR | |
| SCHEMBL10087896 | 0.71 | FFAR3 (0.37) | TSHR | |
| SCHEMBL6623048 | 0.70 | CYP2C19 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611086-A1 | BIPHENYLCARBOXYLIC AMIDE DERIVATIVES AS P38 KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2004089876-A1 | BIPHENYLCARBOXYLIC AMIDE DERIVATIVES AS P38 KINEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-10-21 | — | — | WO | disclosed |