Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052834 | 0.98 | CYP19A1 (0.33) | CYP19A1SCN1ASCN2ASCN3A | |
| SCHEMBL10922421 | 0.75 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL5677016 | 0.75 | TSHR (0.31) | — | |
| SCHEMBL133874 | 0.74 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL4675178 | 0.74 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL4671938 | 0.74 | CYP19A1 (0.30) | CYP19A1 | |
| SCHEMBL4945544 | 0.73 | ALDH1A1 (0.35) | CYP19A1SCN1ASCN2ASCN3A | |
| SCHEMBL1913377 | 0.73 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL9123239 | 0.73 | CTSK (0.33) | — | |
| SCHEMBL18547473 | 0.73 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119779-B2 | Phosphoramidate derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED | 2012-02-21 | — | — | US | disclosed |
| US-20070275910-A1 | Phosphoramidate Derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275910-A1 | Phosphoramidate Derivatives | HRH4, HRH3, NR1H4 | CYP19A1 978/4885SCN1A 3314/4885SCN2A 2500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.