Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680395 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BPYGL | |
| SCHEMBL5677261 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2B | |
| SCHEMBL7255843 | 0.77 | ITGB3 (0.63) | ITGB3ITGA2BMMP2MMP13 | |
| SCHEMBL6885051 | 0.74 | KDM4E (0.67) | — | |
| SCHEMBL21822116 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2B | |
| SCHEMBL15478837 | 0.73 | EGFR (0.57) | ITGB3ITGA2BMMP2MMP13PYGL | |
| SCHEMBL5896939 | 0.71 | ITGB3 (0.60) | ITGB3ITGA2BMMP2MMP13 | |
| SCHEMBL2760120 | 0.71 | MLLT1 (0.66) | PYGL | |
| SCHEMBL1651087 | 0.70 | MMP2 (0.66) | ITGB3ITGA2BMMP2MMP13 | |
| SCHEMBL5897019 | 0.70 | HDAC2 (0.44) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556035-A4 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECH INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1556035-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026264-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |