Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5677209 | 1.00 | MAOB (0.62) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL9369351 | 0.87 | NPC1 (0.52) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL29396289 | 0.87 | NPC1 (0.52) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL3307087 | 0.87 | NPC1 (0.52) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL25195900 | 0.80 | CXCL12 (0.65) | MAOBMAPTMEN1KMT2ATNFRSF1A | |
| SCHEMBL5915740 | 0.79 | MAOB (0.61) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL9852303 | 0.77 | MAOB (0.74) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL5599177 | 0.77 | MAOB (0.74) | MAOBMAPTMEN1KMT2ALMNA | |
| SCHEMBL3123182 | 0.77 | PTGER3 (0.63) | PTGER4PTGER3PTGER2NFKB1 | |
| SCHEMBL30739304 | 0.77 | MAPT (0.45) | MAOBMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | disclosed |