Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.74 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.74 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.74 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.67 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.66 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.66 |
| ▸ | F3 | P13726 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599177 | 1.00 | MAOB (0.74) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL5355811 | 0.88 | MCL1 (0.76) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL4139154 | 0.85 | GABRA3 (0.78) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL28339980 | 0.85 | GABRA3 (0.78) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL3304937 | 0.84 | MAOB (0.69) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL29837036 | 0.84 | MAOB (0.69) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL21647125 | 0.84 | MAOB (0.69) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL14315262 | 0.84 | MAOB (0.72) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL28622228 | 0.84 | MAOB (1.00) | MAOBGABRA3GABRA2GABRB2MAPT | |
| SCHEMBL5479178 | 0.84 | MAOB (1.00) | MAOBGABRA3GABRA2GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428398-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |
| US-4867964-A | SUNSCREEN | L'OREAL (FR) | 1989-09-19 | — | — | US | claimed |
| CN-116162079-B | Synthesis method of aminocoumarin compound | 浙江工业大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-116162079-A | Synthesis method of aminocoumarin compound | 浙江工业大学 | 2023-05-26 | — | — | CN | disclosed |
| US-11485722-B2 | Cyclopenta[c]chromium compound and preparation method therefor | SOOCHOW UNIVERSITY (CN) | 2022-11-01 | — | — | US | disclosed |
| CN-108774207-B | Cyclopenta [ c ] chromene compounds and process for preparing the same | 苏州大学张家港工业技术研究院 | 2021-12-17 | — | — | CN | disclosed |
| US-20210147376-A1 | CYCLOPENTA[C]CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | SOOCHOW UNIVERSITY (CN) | 2021-05-20 | — | — | US | disclosed |
| WO-2020024099-A1 | CYCLOPENTADIENYL [C] CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | 苏州大学张家港工业技术研究院 | 2020-02-06 | — | — | WO | disclosed |
| US-10098853-B2 | Composition for treating atherosclerosis and a preparation method thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2018-10-16 | — | — | US | disclosed |
| US-9085520-B2 | Composition for treating diabetes and metabolic diseases and a preparation method thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2015-07-21 | — | — | US | disclosed |
| US-20140350304-A1 | COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-11-27 | — | — | US | disclosed |
| US-20140194474-A1 | COMPOSITION FOR TREATING ATHEROSCLEROSIS AND A PREPARATION METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-07-10 | — | — | US | disclosed |
| US-20130040996-A1 | COMPOSITION FOR TREATING ATHEROSCLEROSIS AND A PREPARATION METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-14 | — | — | US | disclosed |
| WO-2013022951-A1 | COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-14 | — | — | WO | disclosed |
| US-4867964-A | SUNSCREEN | L'OREAL (FR) | 1989-09-19 | — | — | US | disclosed |
| US-4461907-A | Amino-substituted flavans useful as anti-viral agents | BURROUGHS WELLCOME CO. | 1984-07-24 | — | — | US | disclosed |
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | disclosed |
| EP-0051061-A2 | Novel intermediates and process for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-05-05 | — | — | EP | disclosed |
| EP-0004579-A1 | Flavans, process for their preparation and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147376-A1 | CYCLOPENTA[C]CHROMIUM COMPOUND AND PREPARATION METHOD THEREFOR | CDYL, LAS1L, YAP1 | MAOB 3805/4885GABRA3 3852/4885GABRA2 4025/4885 |
| US-20130040996-A1 | COMPOSITION FOR TREATING ATHEROSCLEROSIS AND A PREPARATION METHOD THEREOF | CDK4, PPARD, CCND1 | MAOB 3661/4885GABRA3 4834/4885GABRA2 4858/4885 |
| US-10098853-B2 | Composition for treating atherosclerosis and a preparation method thereof | CDK4, PPARD, CCND1 | MAOB 3661/4885GABRA3 4834/4885GABRA2 4858/4885 |
| US-20140194474-A1 | COMPOSITION FOR TREATING ATHEROSCLEROSIS AND A PREPARATION METHOD THEREOF | CDK4, PPARD, CCND1 | MAOB 3661/4885GABRA3 4834/4885GABRA2 4858/4885 |
| US-20140350304-A1 | COMPOSITION FOR TREATING DIABETES AND METABOLIC DISEASES AND A PREPARATION METHOD THEREOF | FABP1, GYS2, CYP7B1 | MAOB 3332/4885GABRA3 4084/4885GABRA2 4303/4885 |
| US-11485722-B2 | Cyclopenta[c]chromium compound and preparation method therefor | CDYL, LAS1L, YAP1 | MAOB 3805/4885GABRA3 3852/4885GABRA2 4025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.