Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680907 | 0.77 | APP (0.41) | APPLOXL2CA1CA2CA7 | |
| SCHEMBL7408357 | 0.77 | APP (0.41) | APPAOC3LOXL2CA1CA2 | |
| Hydrochloric Acid SCHEMBL11757860 | 0.74 | APP (0.39) | APPAOC3LOXL2CA1CA2 | |
| SCHEMBL1547810 | 0.72 | APP (0.48) | APPAOC3LOXL2CA1CA2 | |
| SCHEMBL12281853 | 0.72 | ALDH1A1 (0.50) | CA1CA2CA7CA9ACHE | |
| SCHEMBL10585602 | 0.72 | KIF11 (0.43) | CA1CA2CA9TAAR1IDO1 | |
| SCHEMBL991345 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL14761607 | 0.70 | APP (0.46) | APPAOC3LOXL2CA1CA2 | |
| SCHEMBL4305587 | 0.69 | APP (0.44) | APPLOXL2CA1CA2CA7 | |
| SCHEMBL20077315 | 0.69 | APP (0.44) | APPLOXL2CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071500-A | Process for preparing 5-hydroxyalkyl-substituted 1-phenyl-1, 2, 4-triazole derivatives | 拜耳制药股份公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-105130910-A | One-pot synthesis method of epidermal growth factor receptor tyrosine kinase inhibitor PD153035 and its analogue | UNIV ZUNYI MEDICAL | 2015-12-09 | — | — | CN | disclosed |
| WO-2011117798-A1 | 3-(HETEROARYL-AMINO)-1,2,3,4-TETRAHYDRO-9H-CARBAZOLE DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-09-29 | — | — | WO | disclosed |
| EP-1622861-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004101496-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2004-11-25 | — | — | WO | disclosed |
| CN-1036304-C | Phenyltriazole derivatives and insecticides | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1997-11-05 | — | — | CN | disclosed |
| CN-88101620-A | phenyl triazole derivatives and insecticides | — | 1988-10-19 | — | — | CN | disclosed |