Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30175940 | 0.84 | KDM4E (0.87) | KDM4EALDH1A1HSD17B10MAPTCYP1A2 | |
| SCHEMBL14006089 | 0.81 | KDM4E (0.85) | KDM4EALDH1A1HSD17B10MAPTDRD3 | |
| SCHEMBL2760134 | 0.79 | KDM4E (0.74) | KDM4EALDH1A1HSD17B10MAPTSYK | |
| SCHEMBL28624628 | 0.77 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10MAPTCYP2D6 | |
| SCHEMBL5896939 | 0.76 | ITGB3 (0.60) | KDM4EHSD17B10ITGB3ITGA2B | |
| SCHEMBL7255843 | 0.76 | ITGB3 (0.63) | ITGB3ITGA2B | |
| SCHEMBL5754456 | 0.75 | CYP2D6 (0.53) | KDM4EALDH1A1MAPTSYKTSHR | |
| SCHEMBL24076760 | 0.75 | SLC6A2 (0.69) | KDM4EHSD17B10 | |
| SCHEMBL30301388 | 0.75 | SLC6A2 (0.69) | KDM4EHSD17B10 | |
| SCHEMBL20267009 | 0.75 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556035-A4 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECH INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1556035-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026264-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |