SCHEMBL5678601

SCHEMBL5678601

CC(=O)C1C2CC3CC(C2)C1C3

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.35
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
P2RX7 Q99572 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1727171 0.80 HSD11B1 (0.45) HSD11B1CYP2C9P2RX7
SCHEMBL20306757 0.79 HSD11B1 (0.40) HSD11B1
SCHEMBL7741675 0.79 POLB (0.38) HSD11B1CYP2C9CYP2C19P2RX7
SCHEMBL14118138 0.71 POLB (0.39) HSD11B1CYP2C9CYP2C19P2RX7
SCHEMBL12576169 0.70 KMT2A (0.42)
SCHEMBL21376838 0.68 CNR1 (0.45) HSD11B1CYP2C9CYP2C19
SCHEMBL14189730 0.67 KMT2A (0.43) CYP2C9CYP2C19
Acetic Acid SCHEMBL14244268 0.66 FFAR3 (0.47) HSD11B1CYP2C9CYP2C19
SCHEMBL8765839 0.65 MEN1 (0.38) HSD11B1CYP2C9CYP2C19
SCHEMBL7258876 0.65 CYP2C9 (0.42) HSD11B1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0908473-B1 Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process SHINETSU CHEMICAL CO (JP) 2006-02-01 EP claimed
EP-0908473-B1 Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process SHINETSU CHEMICAL CO (JP) 2006-02-01 EP disclosed
US-6613844-B2 Polyhydroxystyrene type polymer containing acid labile groups, endcapped and optionally crosslinked; improved alkali dissolution contrast, sensitivity, resolution, plasma etching resistance, heat resistance, and reproducibility SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-09-02 US disclosed
US-20030013832-A1 Novel styrene polymer, chemically amplified positive resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-01-16 US disclosed
US-6384169-B1 POLYHYDROXYSTYRENE WITH ACID LABILE GROUP, MODIFIED AT ENDS WITH ALKYLS, ESTERS OR ALCOHOLS; INCREASED DISSOLUTION RATE, HIGH SENSITIVITY AND RESOLUTION; RESIST PATTERNS HAVE PLASMA ETCHING RESISTANCE, HEAT RESISTANCE, REPRODUCIBILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-07 US disclosed
EP-0908473-A1 Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-04-14 EP disclosed