SCHEMBL5679072

SCHEMBL5679072

CC(C)(C)c1ccc([O-])c(C(C)(C)C)c1.CC(C)(C)c1ccc([O-])c(C(C)(C)C)c1.C[Al+2]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
ALOX15 P16050 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NR1I2 O75469 1/20 0.37
MAPT P10636 3/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.34
TYR P14679 1/20 0.34
NPC1 O15118 1/20 0.34
PLA2G1B P04054 1/20 0.34
NFKB1 P19838 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL7746261 0.93 ALDH1A1 (0.41) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL7743750 0.93 ALDH1A1 (0.41) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL5396186 0.93 ALDH1A1 (0.41) ALDH1A1ALOX15HPGDHSD17B10TDP1
Lithium Ion SCHEMBL7743747 0.93 ALDH1A1 (0.41) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL10874622 0.93 ALDH1A1 (0.41) ALDH1A1ALOX15HPGDHSD17B10TDP1
Hydrochloric Acid SCHEMBL6039934 0.91 ALDH1A1 (0.40) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL4363292 0.88 ALDH1A1 (0.38) ALDH1A1ALOX15HPGDHSD17B10TDP1
Phosphoric Acid SCHEMBL29534935 0.83 NR1I2 (0.39) ALDH1A1ALOX15HPGDHSD17B10TDP1
Phosphoric Acid SCHEMBL27702683 0.83 NR1I2 (0.39) ALDH1A1ALOX15HPGDHSD17B10TDP1
SCHEMBL1451091 0.83 ALDH1A1 (0.34) ALDH1A1ALOX15HPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0510602-B1 Living polymerization method KANSAI PAINT CO LTD (JP) 1996-06-26 EP claimed
EP-0510602-A1 Living polymerization method KANSAI PAINT CO., LTD. (JP) 1992-10-28 EP claimed
EP-1637543-A2 Polymerization process based on atom (or group) transfer radical polymerization Matyjaszewski, Krzysztof (US) 2006-03-22 EP disclosed
EP-0817806-B1 POLYMERIZATION PROCESS BASED ON ATOM (OR GROUP) TRANSFER RADICAL POLYMERIZATION MATYJASZEWSKI KRZYSZTOF (US) 2006-02-08 EP disclosed
US-20050090632-A1 Noel (co) polymers and a novel polymerization process based on atom (or group) transfer radical polymerization CARNEGIE MELLON UNIVERSITY 2005-04-28 US disclosed
US-6844398-B2 Ethylenic copolymer, composition containing said copolymer, and ethylenic copolymer film IDEMITSU KOSAN CO., LTD. (JP) 2005-01-18 US disclosed
US-20030216528-A1 Novel (co)polymers and a novel polymerization process based on atom (or group) transfer radical polymerization CARNEGIE MELLON UNIVERSITY 2003-11-20 US disclosed
US-6624263-B2 Redox reaction between a transition metal for controlled radical polymerization of styrene and/or (meth)acrylates using organic halides as halogen atom transfer initiators and transition metal complexes as a catalyst CARNEGIE MELLON UNIVERSITY 2003-09-23 US disclosed
US-20020193538-A1 Novel (CO) polymers and a novel polymerization process based on atom (or group) transfer radical polymerization CARNEGIE MELLON UNIVERSITY 2002-12-19 US disclosed
US-20020188087-A1 Ethylenic copolymer, composition containing said copolymer, and ethylenic copolymer film IDEMITSU KOSAN CO., LTD. (JP) 2002-12-12 US disclosed
US-6441116-B1 FILM FORMED FROM AN ETHYLENIC COPOLYMER WHICH HAS A NARROW MOLECULAR WEIGHT DISTRIBUTION AND A NARROW BRANCHING DEGREE DISTRIBUTION AND HAS A CONTROLLED COMPOSITIONAL DISTRIBUTION PROFILE, TEAR STRENGTH, HEAT SEALING IDEMITSU KOSAN CO., LTD. (JP) 2002-08-27 US disclosed
US-6407187-B1 PHASE TRANSFER; FREE RADICAL CATALYST CARNEGIE MELLON UNIVERSITY 2002-06-18 US disclosed
US-5763548-A ADDITION POLYMERIZATION USING TRANSITION METAL CATALYSTS CARNEGIE-MELLON UNIVERSITY (US) 1998-06-09 US disclosed
EP-0817806-A4 NOVEL (CO)POLYMERS AND A NOVEL POLYMERIZATION PROCESS BASED ON ATOM (OR GROUP) TRANSFER RADICAL POLYMERIZATION MATYJASZEWSKI KRZYSZTOF (US) 1998-05-27 EP disclosed
EP-0817806-A1 NOVEL (CO)POLYMERS AND A NOVEL POLYMERIZATION PROCESS BASED ON ATOM (OR GROUP) TRANSFER RADICAL POLYMERIZATION Matyjaszewski, Krzysztof (US) 1998-01-14 EP disclosed
WO-1996030421-A1 NOVEL (CO)POLYMERS AND A NOVEL POLYMERIZATION PROCESS BASED ON ATOM (OR GROUP) TRANSFER RADICAL POLYMERIZATION MATYJASZEWSKI KRZYSZTOF (US) 1996-10-03 WO disclosed
EP-0510602-B1 Living polymerization method KANSAI PAINT CO LTD (JP) 1996-06-26 EP disclosed
US-5328970-A Porphyrin complex as catalyst with organo aluminum compounds for polymerization KANSAI PAINT CO., LTD. (JP) 1994-07-12 US disclosed
EP-0510602-A1 Living polymerization method KANSAI PAINT CO., LTD. (JP) 1992-10-28 EP disclosed