Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7616846 | 0.99 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL5679229 | 0.99 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL5679237 | 0.99 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL5680933 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL7621659 | 0.86 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL7788971 | 0.85 | KMT2A (0.60) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL9570550 | 0.81 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL9570672 | 0.81 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL5682930 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL10802880 | 0.80 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | claimed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | claimed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | claimed |
| EP-1144348-B1 | LTA 4 HYDROLASE INHIBITORS | BIOPROJET SOC CIV (FR) | 2006-02-08 | — | — | EP | disclosed |
| EP-1144348-A3 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144348-A2 | LTA 4? HYDROLASE INHIBITORS | BIOPROJET (FR) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000017133-A2 | LTA4 HYDROLASE INHIBITORS | BIOPROJET (FR) | 2000-03-30 | — | — | WO | disclosed |