Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 7/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570550 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL10802880 | 0.94 | ALDH1A1 (0.77) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL16316826 | 0.93 | FAAH (0.68) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9885419 | 0.93 | FAAH (0.68) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL8733277 | 0.93 | FAAH (0.68) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL11111056 | 0.92 | ALDH1A1 (0.80) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL5682930 | 0.92 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3092909 | 0.92 | ALDH1A1 (0.65) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL7491784 | 0.91 | LMNA (0.70) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3223930 | 0.91 | LMNA (0.74) | ALDH1A1LMNAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |