Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.51 |
| ▸ | NCK1 | P16333 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 6/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21800896 | 0.83 | SCN10A (0.42) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL681625 | 0.82 | BACE1 (0.58) | BACE1NCK1PLAUNCF1CTSD | |
| SCHEMBL31091801 | 0.79 | BACE1 (0.58) | BACE1NCK1PLAUNCF1CTSD | |
| SCHEMBL9167387 | 0.78 | ALDH1A1 (0.53) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL23848110 | 0.78 | ABCB11 (0.43) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL22393977 | 0.77 | SCN10A (0.43) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL13399793 | 0.75 | ALDH1A1 (0.53) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL20309118 | 0.75 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL29473917 | 0.75 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL114725 | 0.75 | ALDH1A1 (0.53) | ALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | claimed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | claimed |
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |