Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.59 |
| ▸ | LTA4H | P09960 | 3/20 | 0.57 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412326 | 0.90 | ABCG2 (0.58) | ABCG2LTA4HNR5A1CHRNB2CHRNB4 | |
| SCHEMBL7702904 | 0.88 | APP (0.55) | ABCG2LTA4HNR5A1CHRNB2CHRNB4 | |
| SCHEMBL9016366 | 0.87 | LTA4H (0.72) | ABCG2LTA4HNR5A1RARBAPP | |
| SCHEMBL10576935 | 0.84 | AHR (0.64) | ABCG2LTA4HNR5A1CHRNA7AHR | |
| SCHEMBL2622565 | 0.84 | AHR (0.64) | ABCG2LTA4HNR5A1CHRNA7AHR | |
| SCHEMBL14566123 | 0.83 | NR5A1 (0.83) | LTA4HNR5A1RARBAPPMEN1 | |
| SCHEMBL10357881 | 0.83 | NR5A1 (0.83) | LTA4HNR5A1RARBAPPMEN1 | |
| SCHEMBL840785 | 0.83 | NR5A1 (0.83) | LTA4HNR5A1RARBAPPMEN1 | |
| SCHEMBL840786 | 0.83 | NR5A1 (0.83) | LTA4HNR5A1RARBAPPMEN1 | |
| SCHEMBL6937465 | 0.83 | RARB (0.68) | ABCG2LTA4HNR5A1RARBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908473-B1 | Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process | SHINETSU CHEMICAL CO (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-0908473-A1 | Styrene polymers, chemically-amplified positive resist compositions, their preparation and use in a patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-04-14 | — | — | EP | disclosed |